Osmoprotective Transcription Factor NFAT5/TonEBP Modulates Nuclear Factor-κB Activity
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چکیده
منابع مشابه
Osmoprotective Transcription Factor NFAT5/TonEBP Modulates Nuclear Factor-κB Activity
Tonicity-responsive binding-protein (TonEBP or NFAT5) is a widely expressed transcription factor whose activity is regulated by extracellular tonicity. TonEBP plays a key role in osmoprotection by binding to osmotic response element/TonE elements of genes that counteract the deleterious effects of cell shrinkage. Here, we show that in addition to this "classical" stimulation, TonEBP protects ce...
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ژورنال
عنوان ژورنال: Molecular Biology of the Cell
سال: 2010
ISSN: 1059-1524,1939-4586
DOI: 10.1091/mbc.e10-02-0133